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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
U2AF2
All Species:
22.12
Human Site:
Y152
Identified Species:
44.24
UniProt:
P26368
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26368
NP_001012496.1
475
53501
Y152
T
R
Q
A
R
R
L
Y
V
G
N
I
P
F
G
Chimpanzee
Pan troglodytes
XP_530073
713
78555
R269
L
P
P
T
S
R
P
R
G
A
P
Q
P
R
F
Rhesus Macaque
Macaca mulatta
XP_001091568
467
51268
Y148
T
R
Q
A
R
R
L
Y
V
G
N
I
P
F
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P26369
475
53499
Y152
T
R
Q
A
R
R
L
Y
V
G
N
I
P
F
G
Rat
Rattus norvegicus
Q63285
419
46487
S131
Y
S
S
H
Q
G
C
S
M
W
M
I
Q
H
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080595
456
51328
M150
F
G
I
T
E
E
A
M
M
D
F
F
N
A
Q
Zebra Danio
Brachydanio rerio
NP_991252
475
53612
Y155
T
R
Q
A
R
R
L
Y
V
G
N
I
P
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24562
416
46636
S128
G
L
A
Q
A
A
G
S
P
V
L
A
C
Q
I
Honey Bee
Apis mellifera
XP_623055
432
48801
Q141
E
M
M
E
F
F
N
Q
Q
M
H
L
S
G
L
Nematode Worm
Caenorhab. elegans
P90978
496
55412
Y187
T
C
Q
S
R
R
L
Y
V
G
N
I
P
F
G
Sea Urchin
Strong. purpuratus
XP_001189425
444
50005
M144
F
G
V
T
E
D
A
M
V
E
F
F
N
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L716
589
66297
Y258
T
R
H
A
R
R
V
Y
V
G
G
L
P
P
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.4
87.5
N.A.
N.A.
99.7
20
N.A.
N.A.
N.A.
92
86.3
N.A.
66.7
66.7
51.4
62.9
Protein Similarity:
100
57.2
89.2
N.A.
N.A.
99.7
37.6
N.A.
N.A.
N.A.
94.7
92.2
N.A.
77
77.8
62.5
75.5
P-Site Identity:
100
13.3
100
N.A.
N.A.
100
6.6
N.A.
N.A.
N.A.
0
100
N.A.
0
0
86.6
6.6
P-Site Similarity:
100
13.3
100
N.A.
N.A.
100
20
N.A.
N.A.
N.A.
6.6
100
N.A.
0
13.3
93.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
42
9
9
17
0
0
9
0
9
0
9
0
% A
% Cys:
0
9
0
0
0
0
9
0
0
0
0
0
9
0
9
% C
% Asp:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% D
% Glu:
9
0
0
9
17
9
0
0
0
9
0
0
0
0
0
% E
% Phe:
17
0
0
0
9
9
0
0
0
0
17
17
0
42
9
% F
% Gly:
9
17
0
0
0
9
9
0
9
50
9
0
0
17
42
% G
% His:
0
0
9
9
0
0
0
0
0
0
9
0
0
9
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
50
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
9
9
0
0
0
0
42
0
0
0
9
17
0
0
9
% L
% Met:
0
9
9
0
0
0
0
17
17
9
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
42
0
17
0
0
% N
% Pro:
0
9
9
0
0
0
9
0
9
0
9
0
59
9
0
% P
% Gln:
0
0
42
9
9
0
0
9
9
0
0
9
9
9
9
% Q
% Arg:
0
42
0
0
50
59
0
9
0
0
0
0
0
9
0
% R
% Ser:
0
9
9
9
9
0
0
17
0
0
0
0
9
0
0
% S
% Thr:
50
0
0
25
0
0
0
0
0
0
0
0
0
0
9
% T
% Val:
0
0
9
0
0
0
9
0
59
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _